Trulance is a medication that is used to treat chronic idiopathic constipation, or CIC. It works by increasing the amount of fluid in the intestines, and this in turn helps to stimulate bowel movements.

In addition to treating CIC, Trulance has also been approved for use in adults with irritable bowel syndrome with constipation (IBS-C). This condition affects approximately 10-15% of adults in the United States. IBS-C is characterized by abdominal pain and discomfort, as well as infrequent and difficult-to-pass stools.

So how does Trulance work? In order to understand this question fully, it’s important to first have a basic understanding of how the digestive system functions.

The Digestive System

The Digestive System

The digestive system includes all parts of the body that are involved in turning food into nourishment for our bodies. This process begins in the mouth as we chew our food and continues through various organs such as the esophagus, stomach, small intestine, large intestine (also called the colon), rectum and anus.

The primary function of the intestines is to absorb nutrients from digested food particles while removing waste products which include stool that needs to be eliminated from time-to-time via defecation / passing stools.

What Is Chronic Idiopathic Constipation?

What Is Chronic Idiopathic Constipation?

Chronic idiopathic constipation is a form of constipation where there are no clear underlying medical conditions causing it. It typically manifests itself through symptoms like:

– Passing fewer than three stools per week
– Difficulty during passing motions
– Abdominal bloating or feeling full even after meals
– Straining during motions leading at times bleeding

Treating Chronic Idiopathic Constipation Using Bulk Laxatives:

Bulk laxatives are typically prescribed for people suffering from chronic idiopathic constipation since they cause an increase in bulk/volume within faecal matter thereby easing their ability outwards/peristalsis action; making elimination easier. They work by retaining fluid within the intestines, which leads to softer and bulkier stools that can be passed more easily.

These medications include psyllium husk, methylcellulose or polyethylene glycol; they are typically sold under a variety of names such as Metamucil, Citrucel or MiraLAX amongst others. These types of products do tend to have some associated side effects due to their effect on the body’s pH balance including gas, bloating & cramping sensations in some people who take them frequently.

Trulance And How It Works:

Trulance is different from typical bulk laxatives like psyllium husk. It belongs to a class of medications known as guanylate cyclase-C (GC-C) agonists that target the cells lining your digestive system.

The medication helps activate GC-C receptors inhabiting these cells in your intestine thereby increasing nutrient absorption whilst decreasing sodium levels causing an increase water retention as well – this combination ultimately leading toward more frequent bowel habits with less strain during passing motions . Activation improves intracellular cGMP production, which helps promote muscle contractions and stimulates fluids into the intestinal tract speeding stool passage through and outwards faster amounting fewer chances for fecal impaction.

Key Takeaways:

– Chronic idiopathic constipation occurs when there isn’t any clear reason behind it.
– Fiber-rich foods and bulk-forming laxatives like psyllium husk are commonly used to treat it.
– Trulance works differently than conventional method acting via guanylate cyclase-cagonist receptor activation stimulating motility thru improved hydration & peristalsis facilitating emptying of waste contents

Consult with your doctor before starting any treatment options for chronic idiopathic constipation symptoms since he/she will know best what medication/dosage would be most beneficial given individual medical history/condition(s).
In conclusion, Trulance is a medication designed to treat chronic idiopathic constipation and irritable bowel syndrome with constipation by increasing the fluid in the intestines to stimulate bowel movements. It works differently than conventional bulk laxatives such as psyllium husk by targeting the cells lining the digestive system and activating GC-C receptors, which leads to improved hydration, peristalsis and easier emptying of waste content.

Although Trulance has been approved for use in adults with IBS-C and patients diagnosed with CIC, it is important to consult your healthcare provider before starting any treatment options so that they can determine what medication/dosage would be most beneficial given individual medical history/condition(s). With proper diagnosis and management, people living with chronic idiopathic constipation or irritable bowel syndrome with constipation can lead healthy lives.